2998
826
6
4
858
Cat. No. | Product Name | ||
---|---|---|---|
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; | |||
L3800 | NF-κB 通路分子库 | 729 compounds | |
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6300 | 药食同源库 | 1290 compounds | |
1290 个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6400 | 海洋天然产物库 | 144 compounds | |
144 种海洋来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0081 |
Magrose Beads OH 6B
琼脂糖羟基磁珠 6B |
||
CEPY-0002 |
Human Cystatin E/CST6 ELISA Pair Set
Human Cystatin E/CST6 ELISA 抗体对 |
||
CEKY-0002 |
Human Cystatin E/CST6 ELISA Kit
Human Cystatin E/CST6 ELISA 试剂盒 |
||
C0001 |
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)
蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO) |
Solution (EDT<em>A</em>-Free,100× in DMSO) | Serine prote<em>a</em>ses, <em>A</em>minopeptid<em>a</em>ses, Cysteine prote<em>a</em>ses, <em>A</em>sp<em>a</em>rtic prote<em>a</em>ses |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26629 |
Angstrom6
A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide |
PAI-1 | Metabolism |
Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽,它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性,能通过与 CD44 结合并调节 CD44 介导的细胞信号传导,抑制肿瘤细胞的迁移、侵袭和转移。 | |||
T9553 |
8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid
|
Others | Others |
8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car 是一种 H+/K+ ATPase 抑制剂,IC50=0.38μM。 | |||
T9837 |
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline 是一种有效的 ALK5 抑制剂,IC50 为 7nM。 | |||
T64393 |
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile
|
Others | Others |
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile 是一种生物活性化合物,可用于化学和生命科学领域的研究。 | |||
T21355 |
6-Chloro-1-tetralone
6-Chloro-α-Tetralone,5-CHLORO-L-INDOMONE,6-chloro-3;5-CHLORO-1-INDOMONE,5-CHLORO-1-INDOMONE,6-chloro-3 |
Others | Others |
6-Chloro-1-tetralone (6-chloro-3;5-Chloro-1-Indomone) 是合成药物化合物的重要中间体。 | |||
T3265 |
Azathramycin
Desmethyl Azithromycin,阿奇霉素 A,6-Demethylazithromycin,去甲基阿奇霉素,Azaerythromycin A,Azaerythromycin |
Antibacterial; Antibiotic | Microbiology/Virology |
Azathramycin (Desmethyl Azithromycin) 是一种可靶向核糖体的抗生素。 | |||
T10165L |
5-A-RU hydrochloride
5-Amino-6-(D-ribitylamino)uracil hydrochloride |
Others | Others |
5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) 是细菌核黄素的中间体,可激活粘膜相关不变 T 细胞(MAIT)。5-A-RU 可用于研究乳腺癌和前列腺癌。 | |||
T76341L |
[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine(94596-26-6 Free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
[DPro10] Dynorphin A (1-11)acetate,porcine 是一种高效的 κ-阿片受体激动剂,其 Ki 值为 0.13 nM。[DPro10] Dynorphin A (1-11), porcine 是一种 N-烷基化衍生物,具有镇痛活性。 | |||
T60098 |
MSC2504877
3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one |
Others | Others |
MSC2504877 是一种tankyrase 抑制剂,可增强临床CDK4/6 抑制剂的作用。 MSC2504877 抑制由 palbociclib 引起的 Cyclin D2 和 Cyclin E2 的上调,并增强对 phospho-Rb 的抑制。 | |||
T22851 |
ICI 63197
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one,三氮唑嘧啶酮 |
PDE | Metabolism |
ICI 63197 (2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one) 是一种 PDE4 抑制剂。 | |||
T7662 |
α-Demethylnaproxen
|
COX | Immunology/Inflammation; Neuroscience |
α-Demethylnaproxen 是一种 COX 的竞争性抑制剂(羊 COX-1 和 -2 的 Ki 值分别为 21 和 19 μM)。 | |||
T40321 | TNF-α-IN-6 | ||
TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM). | |||
T12247 |
NOT Receptor Modulator 1
2-(3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)phenyl)propan-2-ol |
Others | Others |
NOT Receptor Modulator 1 (2-(3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)phenyl)propan-2-ol) 是核受体 NOT 调节剂。 | |||
T12222 |
Nifedipine-d6
硝苯地平 D6,Nifedipine D6,BAY-a-1040 D6 |
Others | Others |
Nifedipine D6 is deuterium labeled nifedipine which is a potent blocker of calcium channel. | |||
T77685 |
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
|
PDK | PI3K/Akt/mTOR signaling |
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 是一种 PDK1 抑制剂,具有抗癌和抗增殖活性,可用来研究血管肉瘤、腺癌、多骨髓瘤、牛皮癣、前列腺癌和和阿尔茨海默病。 | |||
T10180 |
6-Alpha Naloxol
Alpha-Naloxol |
Others | Others |
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist and is a human metabolite of naloxone. | |||
T60008 |
BCL6-IN-6
|
BCL | Apoptosis |
BCL6-IN-6 是 Bcl-6 的抑制剂,可用于关于弥漫性大 B 细胞淋巴瘤的研究。 BCL6-IN-6 阻断 Bcl-6 与其辅阻遏物的相互作用,并以剂量依赖性方式重新激活 Bcl-6 靶基因。 | |||
T10165 |
5-A-RU
5-Amino-6-(D-ribitylamino)uracil |
Others | Others |
5-A-RU (5-Amino-6-(D-ribitylamino)uracil), a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules that are derived from | |||
T20396 |
Levadopa Related Compound A
6-Hydroxydopa, L-,L-Hydroxydopa |
||
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot | |||
T3080 |
Pyridone 6
Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,吡啶酮6,JAK Inhibitor I |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Pyridone 6 (JAK Inhibitor) 是一种泛JAK 抑制剂,有效抑制 JAK 激酶家族,对JAK2、TYK2、JAK3和JAK1的IC50分别为 1、1、5 和 15 nM。 | |||
T39957 |
CDK4/6-IN-6
|
CDK | Cell Cycle/Checkpoint |
CDK4/6-IN-6 是CDK4/CDK6的有效抑制剂,结合CDK4/Cyclin D1 和 CDK6/Cyclin D3 的 Ki 为 0.6 nM 和 13.9 nM。 | |||
T6324 |
(E/Z)-BIX02188
334949-59-6 |
ERK; MEK; TGF-beta/Smad | MAPK; Stem Cells |
BIX02188 是一种特异性 MEK5 抑制剂 (IC50: 4.3 nM),也抑制 ERK5 催化活性 (IC50: 810 nM),并且不抑制密切相关的激酶 MEK1/2、JNK2 和 ERK2。 | |||
T7470 |
6-Chloropurine
6-氯嘌呤,6-Chloro-9H-purine |
Others | Others |
6-Chloropurine (6-Chloro-9H-purine) 是一种制备9-烷基嘌呤和6-巯基嘌呤的中间体,是化学合成的砌块,具有抗肿瘤作用。 | |||
T22530 |
6-Chloromelatonin
|
Melatonin Receptor; Dopamine Receptor | GPCR/G Protein; Neuroscience |
6-Chloromelatonin 是一种有效的褪黑素受体 (melatonin receptor) 激动剂,是一种5-甲氧基吲哚化合物,可竞争兔视网膜中相同的突触前褪黑激素受体位点 ,可抑制[3H]多巴胺的钙依赖性释放 具有比褪黑素更高的代谢稳定性。6-Chloromelatonin 竞争 [3H] 褪黑素 与 MT2 受体结合 (pKi=9.77),可能用于研究与抑郁症相关的失眠和睡眠障碍。 | |||
T19464 |
N6,N6-Dimethyladenosine
N6,N6-二甲基腺苷 |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
N6,N6-Dimethyladenosine 是存在于牛分枝杆菌 tRNA 中的一种修饰核糖核苷 | |||
T18892 |
5(6)-Aminofluorescein
5(6)-氨基荧光素,Fluoresceinamine mixed isomers,5(6)-AFM |
Others | Others |
5(6)-Aminofluorescein (5(6)-AFM) 是一种合成 5(6)-FITC 的前体。其中5(6)-FITC 是胺活性衍生物的荧光染料。 | |||
TP2425 |
Cucumarioside A6-2
|
||
Cucumarioside A6-2 is a triterpene glycoside. | |||
T19618 |
(R)-(-)-JQ1 Enantiomer
(R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
(R)-(-)-JQ1 Enantiomer 是 (+)-JQ1 的立体异构体。 (+)-JQ1 是一种 BET 溴结构域抑制剂,对BRD4(1/2)的IC50 为 77 和 33 nM。 | |||
T36572 |
N6-Methyladenine
6-(甲氨基)嘌呤,N6-Methyladenine,6-(Methylamino)Purine |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
N6-Methyladenine (6-(Methylamino)Purine) 是一种修饰的嘌呤,常见于原核生物、原生生物和植物的基因组中。 N6-Methyladenine 影响多种 DNA 功能,包括复制、修复和表达。 | |||
T21890 |
JLK6
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
JLK-6 是一种γ分泌酶抑制剂,选择性作用于 HEK293细胞的淀粉样β前体蛋白(APP)的γ-分泌酶裂解 APP,抑制 Aβ的生成,但对不 Notch 受体的裂解无影响。 | |||
T26078 |
Rhodblock 6
Rhodblock6,Rhodblock-6 |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Rhodblock 6 是一种 Rho 激酶 (ROCK) 抑制剂,可抑制磷酸化 MRLC(肌球蛋白调节轻链)定位,通过特异性抑制 Rho 激酶的活性发挥作用。 | |||
T7826 |
6-Chloropurine riboside
|
Others | Others |
6-Chloropurine riboside (6-CPR)是一种嘌呤核苷类似物,已被发现具有广泛的生物活性。它可以抑制肿瘤细胞的生长并诱导其凋亡,还被证明具有抗炎、抗病毒和抗真菌的特性,也被发现具有神经保护作用,并已用于治疗神经疾病。 | |||
T16436 |
PBOX 6
PBOX-6 |
Apoptosis | Apoptosis |
PBOX 6 是一种 pyrrolo-1,5-benzoxazepine (PBOX) 化合物,具有抗癌抗肿瘤活性,可在体外抑制乳腺癌细胞的生长,在白血病细胞中通过 c-Jun NH2 末端激酶依赖性磷酸化、 Bcl-2 和 Bcl-XL 的失活发生选择性诱导细胞凋亡。 | |||
T18900 |
6-Aminofluorescein
6-AF,6-氨基荧光素 |
Others | Others |
6-Aminofluorescein (6-AF) 是新型的荧光标记物。 | |||
T18902 |
6-FAM
6-Carboxyfluorescein,6-羧基荧光素 |
Others | Others |
6-FAM (6-Carboxyfluorescein) 是一种羧基荧光素的同分异构体,常用作核酸的测序和标记。 | |||
T7545 |
6-Aminonicotinamide
|
Others | Others |
6-Aminonicotinamide 是一种竞争性 NADP+依赖性酶,是一种烟酰胺抗代谢药,葡萄糖 6-磷酸脱氢酶抑制剂 (Ki=0.46 μM)。 它干扰糖酵解,导致 ATP 耗竭,并与 DNA 交联化学疗法药物,如Cisplatin,协同杀死癌细胞。 | |||
T18893 |
5(6)-Carboxyfluorescein
5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM |
Others | Others |
5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) 是一种胺反应性 pH 敏感的绿色荧光标记物,能够标记蛋白质、多肽和氨基酸,可用于体内实验检测肿瘤位置。 | |||
T72053 |
PERK-IN-6
|
PERK | Apoptosis |
PERK-IN-6 是一种新型高效的 PERK 抑制剂(IC50 : 2.5 nM)。 | |||
T8637 |
DMNB
6-Nitroveratraldehyde,6-硝基藜芦醛 |
DNA-PK | DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
DMNB (6-Nitroveratraldehyde) 可用于合成no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA)。它可用于研究多巴胺能系统的PET。 | |||
T0010 |
6-Mercaptopurine
6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤 |
Nucleoside Antimetabolite/Analog; Others; Dehydrogenase; Endogenous Metabolite; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others |
6-Mercaptopurine (6-MP) 是一种具有免疫抑制特性的抗代谢物抗肿瘤剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。 | |||
T18899L |
5(6)-TAMRA hydrochloride(98181-63-6 Free base)
|
||
5(6)-TAMRA hydrochloride(98181-63-6 Free base) 含有一种羧酸,可通过羧酸的碳二亚胺活化与伯胺反应。 | |||
T60143 |
MitoBloCK-6
|
Apoptosis | Apoptosis |
MitoBloCK-6 是一种有效的Erv1/ALR 抑制剂,IC50分别为 900 nM 和 700 nM。MitoBloCK-6 还抑制Erv2,IC50值为1.4 μM。MitoBloCK-6 可通过释放细胞色素 c 诱导 hESCs 细胞凋亡。 | |||
T39988 |
6'-GNTI dihydrochloride
|
Opioid Receptor; Akt | Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Neuroscience; PI3K/Akt/mTOR signaling |
6'-GNTI dihydrochloride 是一种κ-阿片受体(KOR)激动剂,它偏向于激活 G 蛋白介导的信号传导,而不是β-阿司匹林2的募集。6'-GNTI dihydrochloride 只能激活纹状体神经元中的 Akt 通路。 | |||
T6428 |
BV6
|
IAP | Apoptosis |
BV6 是 c-IAP1 和 XIAP 的拮抗剂,它们是凋亡抑制剂 (IAP) 家族的成员。 | |||
T36466 |
Chlorin E6
Ce6,Chlorin e6,CE6 |
Parasite | Microbiology/Virology |
Chlorin E6 (CE6) 是一种第二代光敏剂,在与辐照结合使用时具有抗肿瘤活性。在植入性纤维肉瘤的小鼠模型中,Chlorin E6(2.5-10 毫克/千克,静脉注射,50-200 焦耳/平方厘米的辐照)在不同程度的辐照后会导致肿瘤完全消失。在一项针对支气管源性早期浅表鳞状细胞癌患者的 I 期临床研究中,对包括 Chlorin E6 在内的制剂进行了测试,结果良好(40 毫克/平方米,静脉注射,100 焦耳/平方厘米的激光辐照)。在一项针对早期肺癌患者的二期临床试验中,同样的给药模式使 82.9% 的患者获得了完全应答。Chlorin E6 已被研究为一种纳米技术给药工具。 | |||
T14204 |
6-Iodopravadoline
[6-碘-2-甲基-1-[2-(4-吗啉基)乙基]-1H-吲哚-3-基](4-甲氧基苯基)甲酮,AM630 |
Cannabinoid Receptor | GPCR/G Protein |
6-Iodopravadoline (AM630) 是大麻素类CB2受体拮抗剂,其Ki=31.2 nM,选择性是 CB1 受体的 165 倍。它减弱了许多大麻素抑制小鼠离体输精管电诱发抽搐的能力。 | |||
T64370 |
JI6
JAK3 Inhibitor VI |
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
JI6 (JAK3 Inhibitor VI) 是有效的,选择性的和具有口服活性的 FLT3 抑制剂。JI6抑制 FLT3-WT,FLT3-D835Y 和 FLT3-D835H 的 IC50 值分别为 ~40,8 和 4 nM。JI6 对 JAK3 和 c-Kit 也有抑制作用,IC50 值分别为 ~250 和 ~500 nM。JI6 可用于急性髓性白血病的相关研究。 | |||
T19159 |
Mal-β-CD
6-O-alpha-D-Maltosyl-beta-cyclodextrin |
Others | Others |
Mal-β-CD is a cellular cholesterol modifier. It can form a soluble inclusion complex with cholesterol. | |||
T20511 |
6-Thioguanosine
6-Mercaptoguanosine,NSC29422,NSC 29422,NSC-29422 |
Others | Others |
6-Thioguanosine (6-Mercaptoguanosine) 是一种活性核苷,是 Azathioprine 的代谢物,是低分子量凝胶剂。6-Thioguanosine 具有免疫抑制作用,可用于研究RNA 双螺旋结构的形成。 | |||
T12134 |
MYCMI-6
NSC354961 |
Apoptosis; c-Myc | Apoptosis; Cell Cycle/Checkpoint |
MYCMI-6 (NSC-354961) 是一种内源性MYC:MAX 蛋白相互作用抑制剂,选择性结合 MYC bHLHZip 域,Kd 值为 1.6 μM。它阻断 MYC 驱动的转录,以 MYC 依赖性的方式抑制肿瘤细胞的生长 ,诱导细胞凋亡。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S2204 |
Sibiricose A6
西伯利亚远志糖A6 |
Antioxidant | oxidation-reduction |
Sibiricose A6 是一种寡糖酯,分离自Polygalae Radix,具有抗氧化作用。 | |||
T6S1315 |
Oroxylin A
千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether |
Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy | Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology |
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。 | |||
TN1304 |
6-Formyl-isoophiopogonanone A
6-甲酰基-异沿阶草酮 A,6-Aldehydoisoophiopogonanone A,6-醛基异麦冬黄烷酮A |
Others | Others |
6-Aldehydoisoophiopogonanone A is a natural product from Ophiopogon japonicus. | |||
TN3158 | 6-Demethoxycleomiscosin A | Others | Others |
6-Demethoxycleomiscosin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3158,CAS号为 121587-20-0。 | |||
TN5470 |
6-Aldehydo-isoophiopogonone A
|
||
6-Aldehydo-isoophiopogonone A是一种天然产物,属于百合科沿阶草属,其产品编号为 TN5470,CAS号为 112500-90-0。6-Aldehydo-isoophiopogonone A可用作对照参考。 | |||
TN1149 |
6''-O-acetylsaikosaponin A
|
Others | Others |
6''-O-Acetylsaikosaponin A 是一种分离自柴胡根中的乙酰柴胡皂苷,表现出一定的破骨细胞抑制活性。 | |||
TN3157 | 6-Demethoxy-9'-deoxycleomiscosin A | Others | Others |
6-Demethoxy-9'-deoxycleomiscosin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3157,CAS号为 121587-18-6。 | |||
T3S0737 |
Flavokawain A
2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A |
Apoptosis; p38 MAPK | Apoptosis; MAPK |
Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮,是一种抗癌试剂,具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡,有潜力用于膀胱癌的相关研究。 | |||
T34765 |
T6A
N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine |
Others | Others |
T6A (N6-Threonylcarbamoyladenosine) 是一种广泛存在具有普遍保守性的核苷,是修饰所必需的化合物。T6A 存在于负责转运 ANN 密码子的 tRNA 中。 | |||
T3885 |
ROSIRIDIN
6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin |
Others; Monoamine Oxidase | Neuroscience; Others |
Rosiridin (6'-O-Deacetylrosiridoside C) 能够抑制 MAO A 和 MAO B,有潜在的抑郁症和老年性痴呆作用。它在 10 μM 时对 MAO B 的抑制率为 83.8% (pIC50=5.38)。 | |||
T5120 |
Rhamnose
6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。 | |||
TN3068 |
4|A,6|A-Dihydroxyeudesm-11(13)-en-12,8|A-olide
4alpha,6alpha-Dihydroxyeudesm-11(13)-en-12,8beta-olide |
Others | Others |
4|A,6|A-Dihydroxyeudesm-11(13)-en-12,8|A-olide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3068,CAS号为 35001-19-5。 | |||
T7174 |
Urolithin A
尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮 |
Apoptosis; Reactive Oxygen Species; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; Drug Metabolite | Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB |
Urolithin A 是一种鞣花酸的肠道微生物代谢产物,可诱导自噬和凋亡,抑制细胞周期进程,抑制DNA 合成,具有抗炎、抗增殖和抗氧化的特性。 | |||
T0581 |
Isomaltose
D-Isomaltose,6-O-α-D-Glucopyranosyl-D-glucose,低聚异麦芽糖900 |
Others; Endogenous Metabolite | Metabolism; Others |
Isomaltose (D-Isomaltose) 是由两个葡萄糖组成的麦芽糖类似物,能够作为蔗糖的替代物,适合于糖尿病患者及有糖尿病倾向的人群。 | |||
T4875 |
Palatinose hydrate
6-O-α-D-Glucopyranosyl-D-fructose, Isoma,帕拉金糖水合物 |
Others; Endogenous Metabolite | Metabolism; Others |
Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) 是内源性代谢产物的一种。 | |||
T2928 |
α-L-Rhamnose monohydrate
L-Rhamnose monohydrate,L-鼠李糖单水合物,6-deoxy-L-mannose monohydrate,α-L-鼠李糖一水合物 |
Others | Others |
α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) 是植物细胞壁果胶多糖鼠李糖半乳糖醛酸聚糖 1 、鼠李糖半乳糖醛酸聚糖 2 的组分。它也是细菌多糖的组分之一,在致病性方面起重要作用。 | |||
TN6775 |
Acetylcytisine
1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,3-acetyl-1,2,3,4,5,6-hexahydro-, (1R)-,11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene |
Others | Others |
Acetylcytisine (11-Acetyl-6-oxo-7,11-diazatricyclo[7.3.1.0<2,7>]trideca-2,4-diene) 是 Genista tinctoria L. 草药的天然产物。 | |||
T78471 |
α,α-Trehalose 6-phosphate potassium
Tre6P potassium |
Endogenous Metabolite | Metabolism |
α,α-Trehalose 6-phosphate (Tre6P) potassium 是一种α,α′-trehalose的6-磷酸衍生物及内源代谢物。在Tre6P磷酸酶 (T6PP) 的催化下,α,α-Trehalose 6-phosphate可被高效转化为α,α′-trehalose。 | |||
TN2004 |
Obtusin
1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮,决明素 |
MAO; Monoamine Oxidase | Metabolism; Neuroscience |
Obtusin 是来自决明子种子,是一种高度选择性和竞争性的人单胺氧化酶-A 抑制剂,IC50=11.12 μM,Ki=6.15 μM。它在神经退行性疾病,尤其是焦虑和抑郁中起预防作用。 | |||
T5145 |
Oxytocin acetate
Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。 | |||
TN5759 |
Platachromone A
5,7,4'-Trihydroxy-6-isoprenyl-2-styrylchromone |
||
Platachromone A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5759,CAS号为 1606149-62-5。 | |||
TN2035 |
Paeonilactone A
(3R,3AR,6S,7AR)-四氢-6-羟基-3,6-二甲基-2,5(3H,4H)-苯并呋喃二酮,芍药内苷A |
Others | Others |
Paeonilactone A是一种天然产物,属于芍药科芍药属,其产品编号为 TN2035,CAS号为 98751-79-2。Paeonilactone A可用作对照参考。 | |||
TN2119 |
Pulsatilla saponin H
白头翁属皂苷H,白头翁皂苷 H,3-O-Β-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 常春藤配基- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷 |
Others | Others |
Pulsatilla saponin H 是一种从 Pulsatilla koreana 的根中分离出来的天然产物。 | |||
TN2117 |
Pulsatilloside E
3-O-B-D-葡萄糖( 1→4)-[ A -L-鼠李糖(1→2)]- A-L-阿拉伯糖 23-羟基羽扇豆20(29)-烯-28–酸- 28-O-鼠李糖(1→4)葡萄糖(1→6)葡萄糖苷,Pulchinenoside E,白头翁皂苷E |
Others | Others |
Pulsatilloside E (Pulchinenoside E) 是一种从毛茛科白头翁Pulsatilla chinensis (Ranunculaceae)的根中分离出来的天然产物。 | |||
T5682 |
6-Hydroxyindole
|
Others | Others |
6-Hydroxyindole 是白色至浅棕色结晶或结晶性粉末。 | |||
TN7221 |
6-Bromovanillin
|
||
6-Bromovanillin 是一种生化试剂,可用于用于合成caridopa。Caridopa 一种芳香氨基酸脱羧酶抑制剂。 | |||
T1362 |
Hypoxanthine
次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin |
Others; Endogenous Metabolite | Metabolism; Others |
Hypoxanthine (Purin-6-ol),也被称为 purine-6-ol 或 Hyp,是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。 | |||
TN6988 |
Pterine-6-carboxylic acid
6-Carboxypterin |
DNA; PDE | DNA Damage/DNA Repair; Metabolism |
Pterine-6-carboxylic acid (6-Carboxypterin) 是叶酸的光降解产物,可被用作光敏感剂研究UVA 破环DNA 结构的分子机制。 | |||
TN1529 |
Coumarin 6
Coumarin VI,香豆素 6 |
Others | Others |
Coumarin 6 (Coumarin VI) 是一种荧光染料,可作为微粒给药系统中的荧光探针,研究药物给药系统的体内跟踪、细胞摄取和转运机制。 | |||
T4816 |
6-Hydroxynicotinic acid
6-Hydroxypyridine-3-carboxylic acid,6-羟基烟酸,2-Hydroxy-5-pyridinecarboxylic acid |
Others; Endogenous Metabolite | Metabolism; Others |
6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) 用于核磁共振波谱或气相色谱-质谱法诊断尿路感染中的铜绿假单胞菌。在引起尿液感染的常见细菌中,只有铜绿假单胞菌从烟酸中产生6-羟基烟酸。 | |||
T7919 |
6-Aminonicotinic acid
|
Others | Others |
6-Aminonicotinic acid 是一种天然产物。 | |||
T2940 |
6-Hydroxyflavone
6-羟基黄酮,6-HF |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
6-Hydroxyflavone (6-HF) 是天然存在的黄酮化合物,具有抗炎作用。它对牛血红蛋白糖基化具有抑制作用。它能激活 AKT、ERK 1/2、JNK 信号通路,有效促进成骨细胞分化。它能抑制 LPS 诱导的 NO 的产生。 | |||
T8036 |
6-Methylflavone
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
6-Methylflavone 是α1β2γ2L 和α1β2GABAA 受体激活剂。 | |||
T3405 |
[6]-Gingerol
6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚 |
Apoptosis; AMPK | Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
[6]-Gingerol ((S)-(+)-[6]Gingerol) 是一种从生姜中分离的活性物质,具有抗癌,抗炎和抗氧化活性。 | |||
TN7147 |
6-Hydroxyisatin
6-Hydroxy-1H-indole-2,3-dione,ZINC14455608,6-hydroxyindoline-2,3-dione,6-羟基靛红,6-hydroxy-2,3-dihydro-1H-indole-2,3-dione |
Others | Others |
6-Hydroxyisatin (ZINC14455608) 是一种海洋来源的天然产物,存在于 Streptomyces sp.。 | |||
T19344 |
Glycogen, Mussel
α-1,6 葡聚糖,Glycogen |
Endogenous Metabolite | Metabolism |
Glycogen, Mussel 是一种糖酵解的中间产物和高能磷酸盐,它是人类、动物、真菌和细菌的一种能量储存形式。 | |||
T4870 |
Petroselinic acid
5-Heptadecylene-1-carboxylic acid,十八碳6烯酸 |
Endogenous Metabolite | Metabolism |
Petroselinic acid (5-Heptadecylene-1-carboxylic acid) 是一种从芫荽的植物油中得到的油酸异构体。 | |||
TN1308 |
6-Hydroxyflavanone
|
Others; Lipoxygenase; COX; GABA Receptor | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others |
6-Hydroxyflavanone 是从菖蒲叶中提取分离,通过靶向环氧合酶-2(COX-2),5-脂氧合酶(5-LOX)以及阿片类药物和 GABA-A 受体从而具有抗炎和抗神经性疼痛活性。6-Hydroxyflavanone 在链脲佐菌素诱导的糖尿病神经病变模型中具有抗伤害感受特性。 | |||
T10183 |
6-Methoxytricin
|
Others | Others |
6-Methoxytricin is a flavonoid isolated from Artemisia iwayomogi. It is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities (IC50s: 30.29 μM and 134.88 μM). 6-Methoxytricin has potential as an anti-diabetic c | |||
T66582 |
6-Methylnicotinamide
|
Endogenous Metabolite | Metabolism |
6-Methylnicotinamide 是烟酰胺的衍生物,是一种内源性代谢物。在脑出血 (ICH) 急性期, 6-Methylnicotinamide 突然增加会加剧神经损伤。6-Methylnicotinamide 可用于制作共晶体/盐。 | |||
T5S1131 |
Ganoderic acid C6
灵芝酸C6 |
Others | Others |
Ganoderic acid C6 是醛糖还原酶活性的抑制剂。 | |||
T6599 |
N6-methyladenosine
N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A |
Others; Influenza Virus; Endogenous Metabolite | Metabolism; Microbiology/Virology; Others |
N6-methyladenosine (NSC-29409) 是甲基化的腺嘌呤残基,苷是转移核糖核酸降解的内源性尿核苷产物。它是存在于所有高等真核生物中普遍的的信使 RNA 内部修饰,可修饰病毒 RNA,有抗病毒活性。 | |||
TN3174 |
6-Methoxyflavanone
NSC50184 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
6-Methoxyflavanone(6-MeOF)是人重组GABA A受体GABA反应的正变构调节剂,具有抗焦虑活性和抗炎活性,可用于减轻顺铂诱导的神经性疼痛。 | |||
TN7047 |
6-O-Methylcatalpol
|
Others | Others |
6-O-Methylcatalpol 是从 S. ningpoensis 的根中分离得到的天然产物。 | |||
T5647 |
6-Methylcoumarin
Toncarine,6-甲基香豆素 |
Others | Others |
6-Methylcoumarin (Toncarine) 是一种合成香料,广泛用于化妆品中。 | |||
T1004 |
6-Benzylaminopurine
6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine |
Others | Others |
6-Benzylaminopurine (6-BAP) 是一种细胞分裂素,能够通过刺激细胞分裂引起植物生长和发育,抑制呼吸激酶,从而延长绿色蔬菜的保鲜。 | |||
TN1154 |
Nepetin
6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素 |
Calcium Channel; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮,具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。 | |||
T8268 |
6,2'-Dihydroxyflavone
6,2-二羟基黄酮,6,2'-二羟基黄酮 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
6,2'-Dihydroxyflavone 是一种新型GABAA 受体拮抗剂。 | |||
T8878 |
urolithin M6
尿石素M6,3,8,9,10-tetrahydroxy urolithin |
Others | Others |
urolithin M6 (3,8,9,10-tetrahydroxy urolithin) 是一种由肠道微生物群产生的鞣花单宁代谢物,被确定为推定的没食子黄素模拟物。 | |||
T2S0357 |
6-Hydroxycoumarin
6-hydroxychromen-2-one,6-羟基香豆素 |
Others; Carbonic Anhydrase | Metabolism; Others |
6-Hydroxycoumarin (6-hydroxychromen-2-one) 是一种香豆素。其中香豆素具有抗炎,支气管扩张,解热,血管扩张,抗氧化,抗菌,抗真菌,抑菌和抗肿瘤作用。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGA... |
Human | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med... | |||
TMPY-04643 |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
integrin, α5 (fibronectin receptor, α polypeptide),integrin,... |
Mouse | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-med... | |||
TMPJ-00780 |
IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)
Interferon α-K,Interferon α-6,IFN α6,Inter... |
Human | Human Cells |
Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. | |||
TMPY-01809 |
SLAMF6 Protein, Mouse, Recombinant (His)
SF2000,SLAM family member 6,NTB |
Mouse | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cy... | |||
TMPY-01914 |
SLAMF6 Protein, Human, Recombinant (His)
SLAM family member 6,CD352,KA... |
Human | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cy... | |||
TMPY-03766 |
SLAMF6 Protein, Human, Recombinant (hFc)
CD352,NTB-A,NTBA,KALIb,Ly108,K |
Human | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cy... | |||
TMPY-03804 |
SLAMF6 Protein, Human, Recombinant
CD352,KALI,NTB-A,SLAM fa... |
Human | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cy... | |||
TMPY-02158 |
Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His)
Integrin α6 β 1,ITGA6B,VLA |
Human | HEK293 |
Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 198 kDa. Accession number: P23229-3&P05556-1 | |||
TMPJ-00218 |
SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated
CD352,SLAM Family Member 6,A<... |
Human | Human Cells |
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Pho... | |||
TMPY-02617 |
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
NP Protein |
H2N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... | |||
TMPY-05544 |
LY6A Protein, Mouse, Recombinant (His)
Sca-1,lymphocyte antigen 6 comple... |
Mouse | E. coli |
LY6A Protein, Mouse, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 10.9 kDa. Accession number: P05533 | |||
TMPK-00651 |
SLAMF6 Protein, Cynomolgus, Recombinant (His)
SF2000,Ly108,KALIb,SLAMF6,NTB- |
Cynomolgus | HEK293 |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. | |||
TMPK-00222 |
SLAMF6 Protein, Human, Recombinant (His & Avi)
ANK-T-B-antigen,Ly108,KALIb,SL |
Human | HEK293 |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. | |||
TMPJ-01060 |
CXCL6 Protein, Human, Recombinant (His)
SCYB6,Chemokine Alpha 3,CKA |
Human | Human Cells |
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell... | |||
TMPK-01174 |
SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His)
Ly108,ANK-T-B-antigen,NTB-A,K... |
Mouse | HEK293 |
SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be widely and exclusively expressed on hematopoietic cells. The SLAMF6 intracellular portion is characterized by two ITSMs that act as binding sites for adaptor molecules such as SAP and EAT-2. | |||
TMPY-01202 |
Dectin-2 Protein, Mouse, Recombinant (His)
Nkcl,Clec4n,Clecsf10,C-type lectin domain fa |
Mouse | HEK293 |
C-type lectin domain family 4 member N (CLEC4N), also known as Dectin-2, is a C-type lectin expressed by dendritic cells (DCs) and macrophages. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins functionally important in glycoprotein metabolism, mechanisms of multicellular integration and immunity. They share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathoge... | |||
TMPJ-01380 |
ST6GalNAc2 Protein, Human, Recombinant (His)
GalNAc α-2,SIATL1,SIAT7B... |
Human | Human Cells |
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the k... | |||
TMPY-05329 |
Cortisol Binding Globulin Protein, Human, Recombinant (His & Avi), Biotinylated
serpin peptidase inhibitor, clade A |
Human | HEK293 |
Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebrate blood. CBG is specifically cleaved by this protease at a precise site close to its carboxy-terminus. This induces a conformation change and disrupts the binding between glucocorticoids and CBG, and promotes a significant and local release of glucocorticoids (over 90% of them a... | |||
TMPY-02041 |
Cortisol Binding Globulin Protein, Human, Recombinant (His)
CBG,serpin peptidase inhibitor, clade ... |
Human | HEK293 |
Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebrate blood. CBG is specifically cleaved by this protease at a precise site close to its carboxy-terminus. This induces a conformation change and disrupts the binding between glucocorticoids and CBG, and promotes a significant and local release of glucocorticoids (over 90% of them a... | |||
TMPY-01050 |
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
CAD6,cadherin 6, type 2,... |
Human | HEK293 |
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progression in a number of adenocarcinomas. Cadherin-6 (CDH6), also known as K-cadherin (KCAD), is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is syn... | |||
TMPY-03173 |
Dectin-2 Protein, Human, Recombinant (hFc)
CLEC6A,CLEC4N,DECTIN2,CLECSF10,C-type lect... |
Human | HEK293 |
C-type lectin domain family 4 member N (CLEC4N), also known as Dectin-2, is a C-type lectin expressed by dendritic cells (DCs) and macrophages. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins functionally important in glycoprotein metabolism, mechanisms of multicellular integration and immunity. They share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathoge... | |||
TMPY-02800 |
CGB7 Protein, Human, Recombinant (His)
chorionic gonadotropin beta subunit 7,chor... |
Human | Baculovirus-Insect Cells |
CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are... | |||
TMPY-02107 |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His)
SerpinA6,AV104445,AI2 |
Mouse | HEK293 |
Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebrate blood. CBG is specifically cleaved by this protease at a precise site close to its carboxy-terminus. This induces a conformation change and disrupts the binding between glucocorticoids and CBG, and promotes a significant and local release of glucocorticoids (over 90% of them a... | |||
TMPJ-00384 |
PFKM Protein, Human, Recombinant (His)
Phosphofructo-1-kinase isozyme A,Phosphohe... |
Human | Human Cells |
6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. | |||
TMPY-06702 |
Cortisol Binding Globulin Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cbg,AI265318,serpin peptidase inh... |
Mouse | HEK293 |
Corticosteroid-binding globulin (CBG), also known as SerpinA6, is a non-inhibitory member of the serine proteinase inhibitor (serpin) superfamily. It is the high-affinity transport protein for glucocorticoids in vertebrate blood. CBG is specifically cleaved by this protease at a precise site close to its carboxy-terminus. This induces a conformation change and disrupts the binding between glucocorticoids and CBG, and promotes a significant and local release of glucocorticoids (over 90% of them a... | |||
TMPY-03298 |
IL-6 Protein, Rat, Recombinant
白细胞介素,interleukin 6,白介素 |
Rat | E. coli |
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affini... | |||
TMPY-03382 |
FGF-6 Protein, Human, Recombinant
HBGF-6,HST2,fibroblast growth fac... |
Human | E. coli |
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene d... | |||
TMPJ-00538 |
LILRA3/CD85e Protein, Human, Recombinant (His & Avi), Biotinylated
Leukocyte immunoglobulin-like receptor subfamily |
Human | Human Cells |
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural kil... | |||
TMPY-03238 |
IL-6 Protein, Mouse, Recombinant
白介素,Il-6,白细胞介素,interleukin 6 |
Mouse | E. coli |
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affini... | |||
TMPY-03327 |
IL-6 Protein, Rhesus, Recombinant
白介素,interleukin 6,白细胞介素 |
Rhesus | E. coli |
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affini... | |||
TMPY-00863 |
IL-6 Protein, Human, Recombinant
BSF2,白细胞介素,HSF,IL-6,IFNB2,interleukin 6,HG... |
Human | E. coli |
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affini... | |||
TMPY-01822 |
PTK9 Protein, Human, Recombinant (His & GST)
PTK9,MGC41876,A6,MGC23788,twinfil... |
Human | E. coli |
Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1, a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is express... | |||
TMPY-01823 |
PTK9 Protein, Human, Recombinant
MGC41876,twinfilin actin binding protein 1... |
Human | E. coli |
Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1, a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is express... | |||
TMPY-02879 |
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)
interleukin 36, alpha,白细胞介素,FIL1(... |
Human | E. coli |
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. It has been reported that IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB i... | |||
TMPY-01600 |
CLEC4A Protein, Human, Recombinant (His)
CLECSF6,LLIR,CD367,C-type lectin doma<... |
Human | HEK293 |
Dendritic cell immunoreceptor (DCIR), also known as C-type lectin domain family 4 member A (CLEC4A), C-type lectin superfamily member 6 (CLECSF6), is a single-pass type II C-type lectin receptor expressed mainly in dendritic cells (DCs), which is a negative regulator of DC expansion and has a crucial role in maintaining the homeostasis of the immune system. The Dectin-2 family of C-type lectins that includes Dectin-2, BDCA-2, DCIR, DCAR, Clecsf8 and Mincle. These type II receptors contain a sing... | |||
TMPY-02603 |
STAT6 Protein, Human, Recombinant (His)
STAT6C,IL-4-STAT,STAT |
Human | Baculovirus-Insect Cells |
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators... | |||
TMPY-05781 |
LILRA6 Protein, Human, Recombinant (His)
LILRB6,ILT-8,ILT5,LILRB3,ILT8,CD85b |
Human | HEK293 |
LILRA6 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 47.78 kDa. Accession number: Q6PI73-1 | |||
TMPY-00971 |
CEACAM6 Protein, Human, Recombinant (His)
NCA,CD66c,CEA,CEA |
Human | HEK293 |
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of mi... | |||
TMPY-02118 |
IGFBP-6 Protein, Mouse, Recombinant (His)
IGFBP-6,insulin-like growth factor binding... |
Mouse | HEK293 |
Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) bindin... | |||
TMPY-04830 |
GAS6 Protein, Mouse, Recombinant (His)
growth arrest-specific 6,Gas-... |
Mouse | HEK293 |
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor... | |||
TMPY-05850 |
CEACAM6 Protein, Cynomolgus, Recombinant (His)
carcinoembryonic antigen-related ... |
Cynomolgus | HEK293 |
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of mi... | |||
TMPY-01132 |
COL6A3 Protein, Human, Recombinant
collagen, type VI, α3,collagen, type VI, <... |
Human | HEK293 |
COL6A3 Protein, Human, Recombinant is expressed in HEK293 cells. | |||
TMPY-01214 |
IL-6R Protein, Mouse, Recombinant (His)
MGC30256,IL-6R,Il6r,interleukin <... |
Mouse | HEK293 |
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through thi... | |||
TMPY-00369 |
LY6D Protein, Human, Recombinant (mFc)
E48,lymphocyte antigen 6 complex, locus D,... |
Human | HEK293 |
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane protein... | |||
TMPY-00864 |
IL-6R Protein, Human, Recombinant (His)
IL-6R-1,IL-6RA,IL6Q,CD12... |
Human | HEK293 |
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through thi... | |||
TMPY-05278 |
IL-6R Protein, Human, Recombinant (hFc)
IL-6R-1,CD126,gp80,IL6Q,IL6 |
Human | HEK293 |
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through thi... | |||
TMPY-05930 |
Influenza A H1N1 (A/Auckland/6/1996) Neuraminidase/NA (His)
NA Protein |
H1N1 | HEK293 |
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell. Influenza neuraminidase is composed of four identical subunits arranged in a square. It is normally attached to the virus surface through a long protein stalk. The active sites are in a deep depression on the upper surface. They bind to polysaccharide chains and clip off... | |||
TMPY-02371 |
ST6GAL1 Protein, Mouse, Recombinant (His)
ST6 β-galactosamide α-2,... |
Mouse | HEK293 |
Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein that belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally f... | |||
TMPY-06490 |
Influenza A H3N2 (A/Darwin/6/2021) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma vir |
H3N2 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ... | |||
TMPY-06483 |
Influenza A H3N2 (A/Darwin/9/2021)/(A/Darwin/6/2021) Nucleoprotein/NP Protein (His)
NP Protein |
H3N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... | |||
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